What is Nolvadex?

Nolvadex is a hormone receptor-positive (hormone-positive) breast cancer medication. It may also aid in the prevention of breast cancer. Since its approval by the Food and Drug Administration (FDA) in 1998, Nolvadex has been one of the most extensively utilized breast cancer medicines.

Nolvadex or Tamoxifen can reduce the incidence of cancer recurrence and invasive malignancy considerably.  It also helps some women to reduce their risk of breast cancer. The daily oral drug prevents cancer cells from using estrogen and progesterone, preventing them from growing and spreading.

It is also used by bodybuilders to build muscles while reducing water retention and gynecomastia.

Now that you know what is Nolvadex, let’s delve deeper and find out more about this steroid.

What is the mode of action of Nolvadex?

A selective estrogen receptor modulator, like Nolvadex, is a form of hormonal therapy (SERM). In breast cancer cells, the drug binds to hormone receptors (particular proteins). Once inside the cells, the medicine prevents cancer from gaining access to the hormones it needs to replicate and expand.

Uses Of Nolvadex:

 Breast Cancer with Metastatic Spread

Both men and women can benefit from Nolvadex for the treatment of metastatic breast cancer. It is an option for oophorectomy or ovarian irradiation in premenopausal women with metastatic breast cancer. According to existing data, patients with estrogen receptor-positive tumours are more likely to benefit from this treatment.

Breast Cancer Adjuvant Therapy

Following a complete mastectomy or segmental mastectomy, axillary dissection, and breast irradiation, Nolvadex is used to treat node-positive breast cancer in women. The grouping with four or more positive axillary nodes has had the biggest effect in various adjuvant studies.

In individuals taking adjuvant Nolvadex medication for breast cancer, Nolvadex also lowers the risk of contralateral breast cancer.

DCIS (Ductal Carcinoma in Situ)

Following breast surgery and radiation, Nolvadex is used to minimize the risk of invasive breast cancer in women with DCIS. Individual assessments of the advantages and risks of Nolvadex medication for breast cancer prevention should be used to make this decision.

Breast Cancer Incidence Reduction in High-Risk Women

Nolvadex is used to lower the risk of breast cancer in women who are at high risk. This effect was demonstrated in a 5-year trial with a median follow-up of 4.2 years. Twenty-five per cent of the individuals were given the medication for five years. The long-term consequences remain unknown.

Gaining Muscles in Bodybuilding

Does Nolvadex increase testosterone? It is one of the most commonly asked questions related to this steroid.

Bodybuilders benefit from Nolvadex since it increases LH production, which can considerably raise the testosterone level found in the body.

After coming off an anabolic steroid, most bodybuilders use Nolvadex. As a result, the drug is an effective PCT option. However, you must adhere to Nolvadex dosage for PCT to get optimal results.

While the medicine has obvious advantages in terms of lowering estrogen levels in the body, it's important to keep in mind that it can make progesterone-related steroids hazardous.

Nolvadex can be added during the washout cycle because most anabolic steroids decrease testosterone production. Nolvadex is preferred by certain bodybuilders, while Arimidex is preferred by others. Both medicines have similar side effects. Since Nolvadex also inhibits estrogen activity, it is commonly used by bodybuilders to gain muscles while reducing gynecomastia and water retention.

What are some of the other advantages of using Nolvadex?

Nolvadex; Not only does it reduce the chance of breast cancer and cancer recurrence, but it also:

·       After menopause, it helps to prevent bone loss (osteoporosis).

·       It helps to lower cholesterol levels.

How do you take Nolvadex?

Nolvadex should be taken by mouth every day, usually at the same time each day. The medication is available in two forms:

·       Nolvadex® pill.

·       Soltamox® liquid.


How long should you take Nolvadex?

The majority of individuals take Nolvadex or other hormone therapy for at least five years and in rare cases up to ten. The purpose of your use dictates the length of your treatment.

Your doctor may recommend that you use Nolvadex for five years before moving to another hormonal treatment for a timeframe.

Dosage of Nolvadex:

For those consuming Nolvadex for bodybuilding, a daily dose of 20-40 mg is recommended. Doses more than 20 mg should be split into two doses, one in the morning and one in the evening.

In three single-agent adjuvant studies in women, one 10 mg NOLVADEX (tamoxifen citrate) tablet was administered two (ECOG and NATO) or three times a day for two years. In the NSABP B-14 adjuvant study, women with node-negative breast cancer were given one 10 mg NOLVADEX pill twice a day for at least 5 years. Extending treatment beyond five years, according to the findings of the B-14 trial, provided no extra benefit.

The reduction in recurrence and death was greater in studies that used tamoxifen for around 5 years than in studies that used tamoxifen for a shorter term of therapy, according to the EBCTCG 1995 summary. There was no evidence that higher doses of 20 mg per day were more beneficial. Clinical trials currently support adjuvant NOLVADEX (tamoxifen citrate) therapy for patients with breast cancer for 5 years.

Side effects Of Nolvadex:

Adverse responses to Nolvadex are usually minimal and only need therapy termination in rare cases. More information on the incidence of adverse effects with Nolvadex when compared to placebo has come from ongoing clinical research.

You may experience hot flashes, nausea, leg cramps, muscular aches, hair thinning, headaches, and numb/tingling skin. Men may experience a decrease in sexual capacity or interest. Notify your doctor right once if these Nolvadex side effects persist or worsen.

If you have any severe Nolvadex side effects, like vision problems, eye irritation, easy bruising/bleeding, psychotic problems, inflammation of ankles/feet, fatigue, infectious symptoms, or signs of liver disease, contact your doctor straight away.


If you are sensitive to Nolvadex or have other concerns, notify your doctor or pharmacist before taking it. Inactive ingredients in this product may cause allergic reactions or other issues. For further information, talk to your pharmacist.

Blood clots such as deep vein thrombosis, pulmonary embolism, or stroke, high triglycerides, limited or no strength to walk, diabetes, hypertension, smoking, cataracts, or liver illness should all be discussed with your doctor or pharmacist.

Getting pregnant while taking Nolvadex is not a good idea. Nolvadex can be harmful to a baby. It has the potential to induce birth abnormalities. If you're pregnant or trying to get pregnant, you shouldn't take the drug. Consult your doctor about non-hormonal birth control choices to avoid pregnancy. (Hormonal contraceptives have been shown to hasten the progression of hormone-positive breast cancer.) While using Nolvadex and for two months after quitting it, you should use contraception.

Where to buy Nolvadex?

If you are wondering where to buy Nolvadex for bodybuilding, there’s no better option than UGFreak. You will have access to real steroids here at economical rates. However, it’s recommended to do your research pertaining to uses, benefits, and Nolvadex side effects for males and females prior to using it.

Final Thoughts

Nolvadex is a very effective treatment for breast cancer. It has the potential to reduce your chances of a recurrence or aggressive breast cancer. Nolvadex is a drug that can help people who are at high risk for breast cancer lessen their chances of developing the disease. It also has the potential of providing you with muscle gain while preventing water retention. Consult the doctor to help you decide if Nolvadex or another type of hormone therapy is best for you.


What exactly does Nolvadex do?

Nolvadex with the scientific name Tamoxifen is a PCT drug that works to neutralize natural hormone production in humans. It blocks estrogen receptors by binding to them and reduces the risk of breast cancer in males. 

Is Nolvadex a testosterone booster?

No, Nolvadex has nothing to do with Testosterone boosting. It is a SERM or selective Estrogen receptor modulator that works to block estrogen receptors and treat breast cancer by suppressing the growth of cancerous cells. 

What is Nolvadex used for in bodybuilding?

Bodybuilders use Nolvadex as a PCT or post-cycle drug to mitigate the harmful effects of other anabolic steroids. It not only helps bodybuilders to retain muscles after completing the steroid cycle but also suppresses Estrogen production which results in maintaining Testosterone levels in steroid users.  

What is Nolvadex for men?

Nolvadex for men is highly effective to tackle health issues linked to excessive stimulation of Estrogen receptors. It binds to Estrogen and blocks its receptors which reduces the risk of Gynecomastia or enlarged breast tissues in men. 

Can Nolvadex remove Gyno?

Yes, Nolvadex suppresses Estrogen and stops the growth of breast tissues in men that helps in reducing Gynecomastia issues in men because of using steroids in excessive amounts and for long durations. 

Is Nolvadex used for fertility?

Yes, Nolvadex is proved quite effective in various treatments to induce fertility in males. It suppresses Estrogen and increases Testosterone levels which are very useful in treating various infertility and delayed puberty issues in men. 

How quickly does Nolvadex work?

It depends on the dosage and purpose of using Nolvadex. Usually, it takes only a few days to a week to provide noticeable results. 

Does Nolvadex have side effects?

Yes, just like other synthetic drugs, Nolvadex also has serious health risks. Its prolonged usage can adversely increase the risk of blood clots in urine and uterine cancer. 

Some common side effects may include; 

  • Hot flashes 

  • Nausea 

  • Mood swings 

  • Change in Libido

Does Nolvadex increase weight?

No, Nolvadex is not involved in weight gain in any way. If you are experiencing weight gain issues during consumption, it may be due to other factors.